List of psychoactive substances derived from artificial fungi biotransformation
List of psychoactive substances derived from artificial fungi biotransformation. These are novel psychedelics with no human safety data available.
- 4-HO-DET and 4-PO-DET mushrooms derived from Psilocybe cubensis mycelium in substrate with added DET.[1][2]
- 4-HO-DiPT mushrooms derived from Psilocybe cubensis mycelium in substrate with added DiPT.[3]
- 4-HO-DPT mushrooms derived from Psilocybe cubensis mycelium in substrate with added DPT.[3]
- Baeocystin (4-PO-NMT) found in Psilocybe cubensis mushrooms from mycelium in substrate with added NMT.[1]
Substrates suspected to produce neurotoxic compounds
4-PO-5-MeO-DMT and 4-PO-5-HO-DMT may be neurotoxic
Compared to related indoles and tryptamines lacking substitutions at the 5,6-position, these new molecules might possess neurotoxic or convulsive properties due to their structure, suggesting potentially shared negative effects.
- 4-HO-5-MeO-DMT (psilomethoxin) mushrooms derived from Psilocybe cubensis mycelium in substrate with added 5-MeO-DMT.[4][3]
- Uncertain outcome: There's no guarantee this modification will create the intended compound 4-PO-5-HO-DMT (psilomethoxin). Research (see a 2023 preprint) hasn't been able to confirm psilomethoxin production in lab settings.
See also
External links
References
- ↑ 1.0 1.1 Gartz J (1989). "Biotransformation of tryptamine derivatives in mycelial cultures of Psilocybe". Journal of Basic Microbiology. 29 (6): 347–52. doi:10.1002/jobm.3620290608. PMID 2614674. Unknown parameter
|s2cid=ignored (help) - ↑ "Read #16 4-HO-DET | TiHKAL · info". isomerdesign.com.
- ↑ 3.0 3.1 3.2 "Ask Dr. Shulgin Online: 4-Hydroxy-5-methoxy-N,N-dimethyltryptamine, Psilocybe mushrooms, Psilocin" (in English).
- ↑ Julia M, Manoury P, Voillaume MC (1965). "[No 209 - Recherches en série indolique. XIV (*) - Sur des méthoxy-5 hydroxy-4, méthoxy-5 hydroxy-6 et méthoxy-7 hydroxy-6 tryptamines]". Bull Chim Soc Fr (in French): 1417–23.