Talk:SubstanceBox/Doxylamine

Chemical Nomenclature

Common names

Unisom, Doxylamine, Doxylamine succinate, Doxyl

Systematic name

N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine

Class Membership

Psychoactive class

Deliriant

Chemical class

Ethanolamine

Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

⇣ Oral
Dosage
Bioavailability	24.7% ^[1]
Threshold	10 mg
Light	75 - 200 mg
Common	200 - 350 mg
Strong	350 - 600 mg
Heavy	600 mg +
Duration
Total	4 - 8 hours
Onset	20 - 60 minutes
Come up	30 - 90 minutes
Peak	1 - 4 hours
Offset	2 - 3 hours
After effects	2 - 24 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

↑ Andries Pelser, Douw G. Müller, Jeanetta du Plessis, Jan L. du Preez, Colleen Goosen. "Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration in rats". https://onlinelibrary.wiley.com/doi/10.1002/bdd.314

[1] Andries Pelser, Douw G. Müller, Jeanetta du Plessis, Jan L. du Preez, Colleen Goosen. "Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration in rats". https://onlinelibrary.wiley.com/doi/10.1002/bdd.314

[1]