Talk:Blue Lotus - PsychonautWiki

Talk:Blue Lotus

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Nymphaea nouchali var. caerulea (Commonly known as Blue Lotus) is a water lily found throughout most of the eastern half of Africa.

Blue Lotus
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Chemical Nomenclature
Common names Blue Lotus, Nymphaea nouchali var. caerulea, Lotus
Class Membership
Psychoactive class Sedative
Chemical class Morphinans
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.


Smoked
Dosage
Threshold 0.5 - g
Light 0.75 - 1 g
Common 1.25 - 2 g
Strong 2.5 - 3 g
Heavy 5 g +
Duration
Total 6 - 8 hours
Onset 10 - 60 seconds
Come up 5 - 10 minutes
Peak 1 - 2 hours
Offset 2 - 2.5 hours
After effects 6 - 8 hours










DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


The flower has been used for over 2000 years in teas, herbal blends and in perfumes.

Like other species in the genus, the plant contains the psychoactive alkaloid aporphine which is thought to be the main constituent causing the effects of the flower, however, it is more likely a group of aporphine alkaloids are working in conjunction to create the various effects as opposed to just aporphine. High potent extracts when ingested or smoked in high doses are reported to produce euphoria and hallucinations.

History and culture

Blue Lotus is thought to be the primary for the fruit of the lotus tree eaten by the mythical Lotophagi (Lotus Eaters) in Homer's Odyssey. The Lotus Eaters were a race of people living on an island dominated by the lotus tree, after they ate the lotus, they would forget their home and loved ones and long only to stay with their fellow lotus-eaters, falling into a infinite euphoric stupor. Those who ate the plant never cared to report or return.

This lotus has been used to produce perfumes since egyptian times. According to a 2023 preprint study, traces of Peganum harmala, and Blue Lotus were identified in an Egyptian ritual Bes-vase, of the 2nd century BCE

The plant and flower are very prominent and frequent in Ancient Egyptian art, cuisine and perfumes. Blue Lotus flowers have been depicted in numerous stone carvings and paintings, including the walls of the temple of Karnak, and may be associated with rites pertaining to the afterlife. At Heliopolis, the origin of the world was taught to have been when the sun god Ra emerged from a lotus flower growing in "primordial waters". At night, he was believed to retreat into the flower again.

Chemistry

The plant has been found to contain aporphine and similar alkaloids as well as Nuciferine. The effects of Blue Lotus are thought to be down to these compounds but other various Quinoline alkaloids could play a role.

 
The two main active components in Blue Lotus.


Pharmacology

aporphine, thought to be the main active component, dopamine receptor agonist targeting the D1 and D2 receptors. Nuciferine, also a prominent alkaloid, is an antagonist at 5-HT2A, 5-HT2C, and 5-HT2B receptors, but is also a partial agonist at D2, D5, and 5-HT6 receptors, and an agonist at 5-HT1A and D4 receptors. Additionally, it inhibits the dopamine transporter (DAT). The group of alkaloids known as Aporphines cause the effects of Blue Lotus. This group contains many Dopamine agonists, a wide range of Serotonin antagonists and Agonists and various reuptake inhibitors. Apomorphine, the active metabolite of Aporphine, has a catechol structure similar to that of dopamine.

 
The group of alkaloids which create the effects of Blue Lotus.



Subjective effects

Physical effects
 

Visual effects
 

Cognitive effects
 

Auditory effects
 

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index. Additional experience reports can be found here:

Toxicity and harm potential

The toxicity of Blue Lotus is misunderstood and poorly researched. Only the pure alkaloids have been tested with little toxicity, however, mixing Blue Lotus with other substances could present a risk.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

There are no studies on aporphine in animals. However, studies on subcutaneous apomorphine injection, the bioactive form of aporphine, have been carried out. In a 5-day study, mice were administered up to 10 mg/kg apomorphine subcutaneously daily. No adverse effects were observed other than a slight increase in dopamine levels.

Tolerance and addiction potential

Blue Lotus is not thought to be addictive. Its compounds have been used in the treatment of alcohol and morphine addiction.

Dangerous interactions

The main and absolute contraindication to using Blue Lotus, is the concurrent use of adrenergic receptor antagonists; combined, they cause a severe drop in blood pressure and fainting.

L-DOPA and Blue Lotus could pose risks and cause symptoms such as sleepiness, dizziness, runny nose, sweating and tremors. Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

Nymphaea caerulea has been illegal in Latvia since November 2009. It is a schedule 1 drug. Possession of large quantities can be punished by up to 15 years in prison.

Nymphaea caerulea was also banned in Poland in March 2009.

Nymphaea caerulea has been illegal in Russia since April 2009.

Nymphaea caerulea is completely prohibited in the state of Louisiana, making it the only state to ban the flower.

Nymphaea caerulea, if sold for human consumption, could fall under the UK's Psychoactive Substances Act 2016, however, this law is rarely imposed on plants and small scale possession.

See also

External links

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Literature

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References



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