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Main article: Tramadol
Psychoactive class:
Opioids
Chemical class:
Phenylpropylamine
Oral
Thresh
Common
Heavy
25
-
25
-
100
-
250
-
300
mg
Light
Strong
Total
: 6 - 10 hours
Onset
: 15 - 60 minutes
Come up
: 30 - 60 minutes
Peak
: 2 - 6 hours
Offset
: 2 - 4 hours
Harm potential
Moderately addictive with a high potential for abuse
Low toxicity, potentially
lethal
when mixed with
depressants
like
alcohol
or
benzodiazepines
Tolerance
Full tolerance is reached develops with prolonged and repeated use
Decreases to half after 3 - 7 days
Returns to baseline after 1 - 2 weeks
Cross-tolerance with all other
opioids
Physical effects
Stimulation
Appetite suppression
Cough suppression
Pain relief
Sedation
Constipation
Dehydration
Difficulty urinating
Headache
Itchiness
Muscle twitching
Nausea
Restless legs
Seizure
Cognitive effects
Cognitive euphoria
Compulsive redosing
Empathy, affection and sociability enhancement
Increased music appreciation
Motivation enhancement
Anxiety suppression
Disinhibition
See also
Responsible use
Summary index
Subjective effect index
Psychoactive substance index