Diphenhydramine/Summary
Harm potential 
-
- Produces dependence with chronic use
- Fatal at amounts close to or exceeding 2 grams
Tolerance 
-
- Full tolerance is reached with repeated use
- Returns to baseline after 1 - 2 weeks
- Cross-tolerance with all deliriants
Physical effects 
-
- Abnormal heartbeat
- Decreased blood pressure
- Dehydration
- Difficulty urinating
- Dizziness
- Dry mouth
- Frequent urination
- Increased bodily temperature
- Increased heart rate
- Increased perspiration
- Itchiness
- Muscle cramp
- Muscle twitching
- Nausea
- Physical fatigue
- Restless legs
- Skin flushing
- Teeth grinding
- Temperature regulation suppression
- Temporary erectile dysfunction
