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Temperature regulation suppression

Temperature regulation suppression can be defined as an inability to maintain a normal temperature. This results in feelings of constantly fluctuating between being uncomfortably cold[1] and uncomfortably hot. At points, this can even result in the sensation of being uncomfortably warm and cold simultaneously.

Temperature regulation suppresion is often accompanied by other coinciding effects such as stimulation and increased perspiration. It is most commonly induced under the influence of heavy dosages of stimulating psychedelic compounds, such as LSD, 2C-B, and AMT. However, it can also occur under the influence of stimulants such as MDMA and methamphetamine.

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References

  1. Walsh, S. L., Strain, E. C., Abreu, M. E., & Bigelow, G. E. (2001). Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans. Psychopharmacology, 157(2), 151-162. https://doi.org/10.1007/s002130100788