Talk:Passionflower

The passion flower was discovered by the Spanish doctor, Monardes in Peru in 1569. Forty years later, it was introduced to Europe as an ornamental plant . Passionflower is native in the south-eastern parts of the US where it had been traditionally used by natives. Today it is spread and cultivated around the world. Historically, the plant has been used as a herbal medicine and entheogen. It is nowadays used to to enhance dreaming because it is thought to be an oneirogen.

Passiflora genus varies greatly in pharmacogicaly active components. Some contain β-carboline-based reversible MAO inhibition. Passiflora incarnata is widely used as a sleep-aid and neurosis OTC treatment. Mithridatum (talk) 15:40, 28 September 2021 (UTC)

Passionflower is a GABA_A & GABA_B ^[1] agonist as well as a MAO(monoamine oxidase) inhibitor. It is thought to have sedative, antioxidative, and anxiolytic qualities.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Combinational effects

• Psychedelics - Passionflower is reported to have a strong synergy with psychedelics, greatly potentiating visual effects.
• Cannabis - Passionflower combined with cannabis is reported to enhance the visual effects and euphoria of cannabis.

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

• Erowid Experience Vaults: Passion Flower

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Dangerous interactions

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit. Combinations with the following substances can cause dangerously high serotonin levels. Serotonin syndrome requires immediate medical attention and can be fatal if left untreated.

• MAOIs - Such as banisteriopsis caapi, syrian rue, phenelzine, selegiline, and moclobemide.^[2]
• Serotonin releasers - Such as MDMA, 4-FA, methamphetamine, methylone and αMT.
• SSRIs - Such as citalopram and sertraline
• SNRIs - Such as tramadol and venlafaxine
• 5-HTP
• Tramadol

• Responsible use

• Passiflora (Wikipedia)
• Passionflower (Erowid Vault)

• APA formatted reference

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