Feelings of impending doom

Feelings of impending doom are defined as the sudden sensations of overwhelming fear and urgency based on the belief that a negative event is about to occur in the immediate future. Negative events typically include some kind of medical emergency, such as the vasovagal response presenting as fainting during a blood donation;^[1] fearing the potential to cause harm to others, being harmed, or dying;^[2] or that the world is coming to an end. This effect can be the result of real evidence, but may also be based on an unfounded delusion or negative hallucinations. The intensity of these feelings can become overwhelming enough to trigger panic attacks.^[3][4]

Feelings of impending doom are often accompanied by vague/paradoxical physical effects^[1] and other coinciding effects such as anxiety, panic attacks,^[5] and unspeakable horrors. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as deliriants like myristicin,^[6][7][8][9] psychedelics,^{[10][11][12][13][14]} and dissociatives. However, they can also occur during medical issues, cardiac arrest, mental illness, or interpersonal problems.