Talk:Microdosing

Microdosing (also known as psychedelic microdosing) is the practice of using sub-threshold doses of a psychedelic substance in an attempt to produce a therapeutic or nootropic effect. Microdosing has been claimed by some to have a wide range of benefits including enhancing productivity, treating symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, boosting creativity and problem-solving abilities, as well as increase spiritual awareness. There is currently no clinical evidence to support these claims, however a number of small scale studies have shown positive outcomes. In 2020 a study by the Beckley Foundation found that a 20 microgram dose of LSD significantly reduced pain perception when compared to a placebo, with results comparable to those observed after administration of opioids.^[1]

While the practice has its origins with LSD, it is in theory possible to microdose with any psychedelic substance. There are a growing body of reports of microdosing psilocybin mushrooms, or psychedelic research chemicals, particularly LSD analogs such as ALD-52, 1P-LSD, AL-LAD and ETH-LAD.

Microdoses range from about one tenth of an active dose. A microdose of LSD is generally considered to be between 5-15 micrograms. This can be measured accurately using volumetric dosing techniques. A microdose of psilocybin mushrooms is harder to determine due to the variations in potency between species and batches; it is generally advised to start with no more than .25g.